Platelet rich plasma for facial rejuvenation: an overview of systematic reviews

Ref ID 1002
First Author M. Cruciani
Journal BLOOD TRANSFUSION
Year Of Publishing 2024
URL https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11390617/
Keywords • Low methodological quality
• Dermatology
• Non-Cochrane reviews
• Cosmetic procedures
Problem(s) • Poor consideration of publication bias
• Reasons for excluding potentially eligible studies not provided
• Incorrect interpretation or statistical inference error from meta-analysis
• Funding or sponsor of systematic review not reported
• Low methodological (AMSTAR) quality
Article Type Empirical
Article Subtype Cross-sectional survey/Methodological systematic review
First Author Country Italy
Checklists • AMSTAR 2
Aim To reappraise the validity of the conclusions of the Systematic Reviews (SRs) and meta-analyses related to platelet rich plasma use for non-surgical treatment of skin aging and facial rejuvenation.
Level of Investigation Descriptive
Summary of Findings Of the 13 included SRs published between 2015 and 2023 on PRP use for facial rejuvenation, none of them reported the details of funding sources, nor assessed publication bias. Only 2 SRs reported a list of excluded studies and reasons for exclusion; meta-analysis was performed with appropriate statistical methods in 2 SRs, but only one did it for outcomes related to facial rejuvenation.
Number of systematic reviews included 13
Number of eligible systematic reviews assessed 328
Treatment impacted No
Treatment impacted description
Interpretation impacted Not Applicable
Interpretation impacted description