Risk factors for cardiovascular diseases in patients with systemic lupus erythematosus: an umbrella review

Ref ID 1027
First Author Y. Katayama
Journal CLINICAL RHEUMATOLOGY
Year Of Publishing 2023
URL https://link.springer.com/article/10.1007/s10067-023-06608-6
Keywords • Low methodological quality
• Cardiology
• Musculoskeletal
• Risk of bias
• Disclosure
• Protocols
Problem(s) • Flawed risk of bias undertaken
• Risk of bias not incorporated into conclusions of review
• Low methodological (AMSTAR) quality
• No registered or published protocol
• Conflicts of interest or funding of included studies not assessed
• Reasons for excluding potentially eligible studies not provided
• Lack of prespecification in eligibility criteria
Article Type Empirical
Article Subtype Cross-sectional survey/Methodological systematic review
First Author Country Japan
Checklists • AMSTAR 2
Aim To provide a comprehensive summary of systematic reviews on risk factors for cardiovascular diseases in patients with systemic lupus erythematosus indexed across PubMed, Embase, and the Cochrane Library from database inception to June 22, 2022.
Level of Investigation Descriptive
Summary of Findings From 9 systematic reviews indexed across PubMed, Embase, and the Cochrane Library from database inception to June 22, 2022. All 9 included systematic reviews (SRs) were assessed as critically low quality according to the AMSTAR 2 tool. Only 2 (22.2%) of the SRs explain their selection of the study designs for inclusion; none of the reviews provided a list of excluded studies with justifications, nor reported on the sources of funding for the included studies. Five reviews (55.5%) did not report prior protocols.and five reviews (55.5) or did not consider the risk of bias in primary studies when interpreting the results of the review. Four reviews (44.4%) did not use an appropriate method to assess the risk of bias.
Number of systematic reviews included 9
Number of eligible systematic reviews assessed 1150
Treatment impacted No
Treatment impacted description
Interpretation impacted Not Applicable
Interpretation impacted description