Efficacy and safety of ozone therapy for knee osteoarthritis: an umbrella review of systematic reviews

Ref ID	1036
First Author	V. T. S. Lino
Journal	FRONTIERS IN PHYSIOLOGY
Year Of Publishing	2024
URL	https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2024.1348028/full
Keywords	Musculoskeletal Low methodological quality
Problem(s)	Low methodological (AMSTAR) quality Risk of bias not incorporated into conclusions of review Funding or sponsor of systematic review not reported Reasons for excluding potentially eligible studies not provided Lack of prespecification in eligibility criteria Insufficient literature searches
Number of systematic reviews included	8
Summary of Findings	The AMSTAR 2 assessments showed that the overall confidence in the results of all eight studies was critically low. None of the reviews explained their selection of the study designs for inclusion, provided a list of excluded studies, or reported on the sources of funding of studies. Half of the reviews did not use a comprehensive search strategy, nor accounted for risk of bias in the individual studies when interpreting/ discussing the results of the review.
Did the article find that the problem(s) led to qualitative changes in interpretation of the results?	Not Applicable
Are the methods of the article described in enough detail to replicate the study?