| Ref ID | 1061 |
| First Author | A. Snellman |
| Journal | SYSTEMATIC REVIEWS |
| Year Of Publishing | 2023 |
| URL | https://systematicreviewsjournal.biomedcentral.com/articles/10.1186/s13643-023-02342-x |
| Keywords |
• Neurology • Risk of bias • Transparency |
| Problem(s) |
• Conflict of interest statement or disclosures for review authors missing • High risk of bias (ROBIS) |
| Article Type | Empirical |
| Article Subtype | Cross-sectional survey/Methodological systematic review |
| First Author Country | Sweden |
| Checklists |
• ROBIS |
| Aim | To compare conflict of interest disclosed by authors of systematic reviews (SRs) of a well-defined clinical topic versus information on financial conflict of interest found in open Internet sources, in relation to risk of bias of systematic reviews indexed across Medline, Cochrane Library, Embase, and PsycINFO in December 2020, investigating the effect of methylphenidate on ADHD . |
| Level of Investigation | Descriptive |
| Summary of Findings | Out of the 44 SRs included, 15 (34%) declared conflict of interest, 27 (61%) did not, and a declaration of conflict of interest was missing for 2 (5%). On open websites, conflict of interest was found for at least one author of 23 (52%) SRs: disclosed in 15 (34%) and not disclosed in 8 (18%) SRs. Seven (16%) SRs had low, 36 (82%) had high, and 1 (2%) had unclear RoB. Among SRs with financial conflict of interest found in open sources, 6/22 (27%) had low RoB compared to 1/21 (5%) if no such conflict of interest was identified. Among SRs with financial conflict of interest identified, 1/6 (17%) at low RoB did not disclose their conflict of interest, whereas the corresponding proportion among SRs at high RoB was 7/16 (44%). |
| Number of systematic reviews included | 44 |
| Number of eligible systematic reviews assessed | 665 |
| Treatment impacted | Not Applicable |
| Treatment impacted description | |
| Interpretation impacted | Not Applicable |
| Interpretation impacted description |