Impact of harm minimization interventions on reducing blood-borne infection transmission and some injecting behaviors among people who inject drugs: an overview and evidence gap mapping

Ref ID 1068
First Author F.S. Tonin
Journal ADDICTION SCIENCE & CLINICAL PRACTICE
Year Of Publishing 2024
URL https://ascpjournal.biomedcentral.com/articles/10.1186/s13722-024-00439-9
Keywords • Low methodological quality
• Public health
Problem(s) • Inadequate analysis of heterogeneity
• Reasons for excluding potentially eligible studies not provided
• Conflicts of interest or funding of included studies not assessed
• Risk of bias not incorporated into conclusions of review
• Low methodological (AMSTAR) quality
Article Type Empirical
Article Subtype Cross-sectional survey/Methodological systematic review
First Author Country Portugal
Checklists • AMSTAR 2
Aim To assess the methodological quality (AMSTAR-2) of systematic reviews of the effectiveness of harm minimization interventions on reducing blood-borne infection transmission and injecting behaviours among people who inject drugs (PWID).
Level of Investigation Descriptive
Summary of Findings The methodological quality assessment of the 33 included systematic reviews using AMSTAR 2 showed that most studies (n = 17; 51.5%) presented low quality. Shortcomings included: 1) not providing the list of excluded studies (20/35, 57.1%); did not employ a technique for assessing the risk of bias in primary studies (13/25, 37.1%); did not report the sources of funding (16/35, 45.7%); account for risk of bias in individual studies when interpreting or discussing the results (item 13); offer explanation for, or discussion of, observed heterogeneity in the results (20/35, 57.1%).
Number of systematic reviews included 33
Number of eligible systematic reviews assessed 275
Treatment impacted Not Applicable
Treatment impacted description
Interpretation impacted Not Applicable
Interpretation impacted description