| Ref ID | 108 |
| First Author | I. X. Y. Wu |
| Journal | THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE |
| Year Of Publishing | 2020 |
| URL | https://journals.sagepub.com/doi/pdf/10.1177/1759720X20959967 |
| Keywords |
• Rheumatology • Searching • Low reporting quality • Protocols • Cochrane • Non-Cochrane reviews • Risk of bias |
| Problem(s) |
• Cochrane reviews more rigorous/higher quality than non-Cochrane reviews • No registered or published protocol • Reasons for excluding potentially eligible studies not provided • Flawed risk of bias undertaken • Low methodological (AMSTAR) quality • Insufficient literature searches |
| Article Type | Empirical |
| Article Subtype | Cross-sectional survey/Methodological systematic review |
| First Author Country | Hong Kong |
| Checklists |
• AMSTAR 2 |
| Aim | To assess the methodological quality (AMSTAR 2) and predictors among systematic reviews of osteoarthritis interventions indexed in three databases from 1 January 2008 to 10 October 2019. |
| Level of Investigation | Descriptive |
| Summary of Findings | Only seven (4.2%) of the included 167 systematic reviews of interventions for osteoarthritis had high methodological quality according to AMSTAR 2. Respectively, eight (4.8%), 25 (15.0%), and 127 (76.0%) systematic reviews had moderate, low, and critically low quality. The main methodological weaknesses were: only 16.8% registered protocol a priori, 4.2% searched literature comprehensively, 25.7% included lists of excluded studies with justifications, and 30.5% assessed risk of bias appropriately by considering allocation concealment, blinding of patients and assessors, random sequence generation and selective reported outcomes. Cochrane reviews [adjusted odds ratio (AOR) 251.5, 95% confidence interval (CI) 35.5–1782.6], being updates of previous SRs (AOR 3.9, 95% CI 1.1–13.7), and SRs published after 2017 (AOR 7.7, 95% CI 2.8–21.5) were positively related to higher methodological quality. |
| Number of systematic reviews included | 167 |
| Number of eligible systematic reviews assessed | 1752 |
| Treatment impacted | No |
| Treatment impacted description | |
| Interpretation impacted | Not Applicable |
| Interpretation impacted description |