Methodologically weak systematic review of Chinese herbal medicine for diabetic peripheral neuropathy calls for more rigorous trials

Ref ID 223
First Author H.B. Xu
Journal FOCUS ON ALTERNATIVE & COMPLEMENTARY THERAPIES
Year Of Publishing 2013
URL https://onlinelibrary.wiley.com/doi/10.1111/fct.12039
Keywords • Heterogeneity
• Low reporting quality
• Searching
• Pre-specification
• Complementary & Alternative
Problem(s) • Individual study characteristics not reported sufficiently
• Errors or omissions in search strategy
• Intervention not described / defined
• Lack of prespecification in eligibility criteria
• Inadequate analysis of heterogeneity
Article Type Editorial
Article Subtype Comment/letter
First Author Country United Kingdom
Aim A commentary highlighting flaws with one systematic review and meta-analysis of Chinese herbal medicine for diabetic peripheral neuropathy published in 2011.
Level of Investigation Descriptive
Summary of Findings The authors highlight that in this one systematic review of Chinese herbal medicine, results from 15 different interventions were pooled into a meta-analysis, ignoring key clinical heterogeneity in the interventions. The authors also highlight that it is not clear how the studies included in the review were selected. Key data about patient characteristics and randomisation in the included trials are missing. Outcome measures are not defined. The search strategy was also too vague to encompass all included interventions and therefore relevant studies may have been missed.
Number of systematic reviews included 1
Number of eligible systematic reviews assessed 1
Treatment impacted No
Treatment impacted description
Interpretation impacted Not Applicable
Interpretation impacted description