The mass production of redundant, misleading, and conflicted systematic reviews and meta‐analyses

Ref ID 301
First Author J. Ioannidis
Journal THE MILBANK QUARTERLY
Year Of Publishing 2016
URL https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020151/pdf/MILQ-94-485.pdf
Keywords • General medical
• Overlapping reviews/redundancy
Problem(s) • Redundant / overlapping / duplicated review question; leads to research waste
Article Type Non-systematic literature review
First Author Country United States
Aim To highlight the huge increase in published systematic reviews since 1991.
Level of Investigation Descriptive
Summary of Findings The authors conduct a search of PubMed to highlight an increase in the publication rate of 2,728% for systematic reviews versus only 153% for all PubMed indexed items between 1991 to 2014. The articles discusses trends in the explosion of publication of meta-analyses more generally but highlights that authors of systematic reviews are increasingly conducted by third-party contractors or consultancy companies, paid for by pharmaceutical companies. These may or may not be published depending on the results.
Number of systematic reviews included 1
Number of eligible systematic reviews assessed 1
Treatment impacted No
Treatment impacted description
Interpretation impacted Not Applicable
Interpretation impacted description