| Ref ID | 342 |
| First Author | N. Koensgen |
| Journal | JOURNAL OF CLINICAL EPIDEMIOLOGY |
| Year Of Publishing | 2019 |
| URL | https://www.jclinepi.com/article/S0895-4356(18)30903-X/fulltext |
| Keywords |
• Pre-specification • General medical • Protocols |
| Problem(s) |
• Undocumented or unjustified deviations to the review protocol |
| Article Type | Empirical |
| Article Subtype | Cross-sectional survey/Methodological systematic review |
| First Author Country | Germany |
| Checklists |
• PRISMA-P |
| Aim | To assess the prevalence of differences in the reported methods between non-Cochrane systematic reviews published up to 2016 and their published protocols and the extent to which these were reported and explained. |
| Level of Investigation | Descriptive |
| Summary of Findings | Almost all included systematic reviews (92.5%) differed from their protocols in at least one of the methods-related PRISMA-P items and their subcategories. Half the systematic reviews (48.8%) had a major difference in at least one item. On average, each systematic reviews differed from its protocol in 3.2 items PRISMA-P, of which one comprised a major difference. Only 10% of all differences were reported in the systematic review, two-thirds with an explanation (7.0% in total) |
| Number of systematic reviews included | 80 |
| Number of eligible systematic reviews assessed | 214 |
| Treatment impacted | No |
| Treatment impacted description | |
| Interpretation impacted | Not Applicable |
| Interpretation impacted description |