| Ref ID | 376 |
| First Author | S. Golder |
| Journal | JOURNAL OF CLINICAL EPIDEMIOLOGY |
| Year Of Publishing | 2013 |
| URL | https://www.jclinepi.com/article/S0895-4356(12)00309-5/pdf |
| Keywords |
• Harms • Cochrane • Reproducibility |
| Problem(s) |
• Reliance on randomised controlled trials for harms / safety data • Methods not described to enable replication |
| Article Type | Empirical |
| Article Subtype | Cross-sectional survey/Methodological systematic review |
| First Author Country | United Kingdom |
| Aim | To assess whether any improvements in the reporting and quality of searching in systematic reviews of adverse effects in the Cochrane database and the Database of abstract of reviews of effects between 1994 and 2011. |
| Level of Investigation | Descriptive |
| Summary of Findings | 5% of reviews in the Cochrane database and the Database of abstract of reviews of effects between 1994 and 2011 focused on adverse effects. Whilst some improvements in literature searches were apparent, such as an increase in the number of databases searched and fewer date and language restrictions applied there was an increase in reviews limited to data from randomized controlled trials. The reporting of search strategies could still be improved further, with only 9% of the included reviews reporting reproducible searches. |
| Number of systematic reviews included | 849 |
| Number of eligible systematic reviews assessed | 15718 |
| Treatment impacted | No |
| Treatment impacted description | |
| Interpretation impacted | Not Applicable |
| Interpretation impacted description |