| Ref ID | 511 |
| First Author | M. J. Page |
| Journal | SYSTEMATIC REVIEWS |
| Year Of Publishing | 2018 |
| URL | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819709/pdf/13643_2018_Article_699.pdf |
| Keywords |
• General medical • Pre-specification • Multiplicity • Protocols |
| Problem(s) |
• Multiplicity of outcomes and lack of pre-specification for outcome reporting |
| Article Type | Empirical |
| Article Subtype | Cross-sectional survey/Methodological systematic review |
| First Author Country | Australia |
| Aim | To assess the number of PROSPERO registrations and website usage from inception to 2017. Epidemiological characteristics of and completeness of primary outcome pre-specification in a random sample of 150 PROSPERO records. |
| Level of Investigation | Descriptive |
| Summary of Findings | There was a 10-fold increase in registrations between 2012 (63 systematic reviews per month) to 2017 (800 per month). No information about the primary outcome other than the domain (e.g. timing, effect measures) was pre-specified in 29% of records. |
| Number of systematic reviews included | 150 |
| Number of eligible systematic reviews assessed | 26535 |
| Treatment impacted | No |
| Treatment impacted description | |
| Interpretation impacted | Not Applicable |
| Interpretation impacted description |