| Ref ID | 518 |
| First Author | C. A. Silagy |
| Journal | JAMA |
| Year Of Publishing | 2002 |
| URL | https://jamanetwork.com/journals/jama/articlepdf/194984/joc11902.pdf |
| Keywords |
• Protocols • Cochrane • General medical |
| Problem(s) |
• Undocumented or unjustified deviations to the review protocol |
| Article Type | Empirical |
| Article Subtype | Cross-sectional survey/Methodological systematic review |
| First Author Country | Australia |
| Aim | To assess the extent to which the content of published Cochrane protocols had change compared with previously published versions of the protocol. |
| Level of Investigation | Descriptive |
| Summary of Findings | 91% of reviews had at least one section that had undergone a major change compared with the most recently published protocol. The greatest variation between protocols and reviews was in the methods section in which 68% of reviews had undergone a major change. The authors highlight that changes made to the protocol that could have been based on prior knowledge of the results are of most concern. |
| Number of systematic reviews included | 47 |
| Number of eligible systematic reviews assessed | 66 |
| Treatment impacted | No |
| Treatment impacted description | |
| Interpretation impacted | Not Applicable |
| Interpretation impacted description |