| Ref ID | 530 |
| First Author | P. Liu |
| Journal | BMC MEDICINE |
| Year Of Publishing | 2019 |
| URL | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805640/pdf/12916_2019_Article_1420.pdf |
| Keywords |
• Cochrane • General medical • Subgroup • Pre-specification • Multiplicity |
| Problem(s) |
• Unplanned or unjustified subgroup or sensitivity analyses • Multiplicity of outcomes and lack of pre-specification for outcome reporting |
| Article Type | Empirical |
| Article Subtype | Cross-sectional survey/Methodological systematic review |
| First Author Country | United States |
| Aim | To assess how often subgroup analyses of age are reported in Cochrane reviews, how often these analyses use formal interaction testing, and other characteristics of the subgroup analyses. |
| Level of Investigation | Descriptive |
| Summary of Findings | 20.4% of the 928 included Cochrane reviews outlined plans to conduct age treatment subgroup analyses. However, 2.7% reviews actually reported age-treatment subgroup analyses. Three reviews performed unplanned age-treatment subgroup analyses. |
| Number of systematic reviews included | 928 |
| Number of eligible systematic reviews assessed | 9073 |
| Treatment impacted | No |
| Treatment impacted description | |
| Interpretation impacted | Not Applicable |
| Interpretation impacted description |