Risk of bias tools in systematic reviews of health interventions: an analysis of PROSPERO-registered protocols

Ref ID 536
First Author K. Farrah
Journal SYSTEMATIC REVIEWS
Year Of Publishing 2019
URL https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857304/pdf/13643_2019_Article_1172.pdf
Keywords • Observational studies
• General medical
• Protocols
Problem(s) • Inclusion of observational / non-randomised studies
Article Type Empirical
Article Subtype Cross-sectional survey/Methodological systematic review
First Author Country Canada
Aim To assess the planned use of risk of bias tools in systematic reviews of health interventions, specifically for reviews that planned to incorporate evidence from randomised controlled trials and/or non-randomised studies.
Level of Investigation Descriptive
Summary of Findings 63% of the 471 included protocols planned to include non-randomised studies as well as randomised controlled trials. The choice of risk of bias tool in protocols that intended to include both randomised controlled trials and non-randomised studies was more heterogeneous indicating lack of consensus on preferred tools for evaluating bias in non-randomised studies.
Number of systematic reviews included 471
Number of eligible systematic reviews assessed 500
Treatment impacted No
Treatment impacted description
Interpretation impacted Not Applicable
Interpretation impacted description