Following 411 Cochrane protocols to completion: a retrospective cohort study

Ref ID 540
First Author A. C. Tricco
Journal PLOS ONE
Year Of Publishing 2008
URL https://pubmed.ncbi.nlm.nih.gov/18997866/
Keywords • General medical
• Currency
• Cochrane
• Protocols
Problem(s) • Unpublished or "zombie" reviews (the file-drawer effect)
• Not updated regularly
Article Type Empirical
Article Subtype Cross-sectional survey/Methodological systematic review
First Author Country Canada
Aim To follow up the frequency of published and unpublished Cochrane reviews from Cochrane protocols that were registered in 2000 and 2001.
Level of Investigation Descriptive
Summary of Findings 19.1% of protocols were not published as full Cochrane reviews by 2008. 80.9% were published in full. Reasons for non-completion included: no reason provided (14.1%), protocol withdrawn due to out-datedness (12.7%), Cochrane review authors lacked time or interest (9.9%), and operational issues (e.g., the lead author changed jobs). Of those completed, only 33.2% had been subsequently updated.
Number of systematic reviews included 372
Number of eligible systematic reviews assessed 411
Treatment impacted No
Treatment impacted description
Interpretation impacted Not Applicable
Interpretation impacted description