| Ref ID | 604 |
| First Author | A. Movsisyan |
| Journal | JOURNAL OF CLINICAL EPIDEMIOLOGY |
| Year Of Publishing | 2016 |
| URL | https://www.jclinepi.com/article/S0895-4356(16)30026-9/abstract |
| Keywords |
• Imprecision • General medical |
| Problem(s) |
• Inflexible methods to complex questions |
| Article Type | Empirical |
| Article Subtype | Cross-sectional survey/Methodological systematic review |
| First Author Country | United Kingdom |
| Aim | To assess the application of the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach and the quality of evidence ratings in Cochrane systematic reviews of complex interventions conducted 2013-2014. |
| Level of Investigation | Descriptive |
| Summary of Findings | The quality of evidence never reached ‘‘high’’ GRADE ratings for the outcomes of complex intervention reviews, compared to simple intervention reviews. Quality ratings were commonly downgraded in the Risk of Bias assessment, particularly for lack of participant and personnel blinding; high levels of heterogeneity, and the study design |
| Number of systematic reviews included | 40 |
| Number of eligible systematic reviews assessed | 279 |
| Treatment impacted | No |
| Treatment impacted description | |
| Interpretation impacted | Not Applicable |
| Interpretation impacted description |