Dealing with effect size multiplicity in systematic reviews and meta‐analyses

Ref ID 656
First Author J. A. López‐López
Journal RESEARCH SYNTHESIS METHODS
Year Of Publishing 2018
URL https://pubmed.ncbi.nlm.nih.gov/29971966/
Keywords • Multiplicity
• Pre-specification
• General medical
Problem(s) • Multiplicity of outcomes and lack of pre-specification for outcome reporting
Article Type Non-systematic literature review
First Author Country UK
Aim To highlight and define multiplicity of effect sizes from the same patient data which can be misleading
Level of Investigation Descriptive
Summary of Findings Twenty six effect sizes are found from one systematic review indicating how substantial multiplicity is possible depending on the review question and careful definition of what data can be pooled
Number of systematic reviews included 1
Number of eligible systematic reviews assessed 1
Treatment impacted No
Treatment impacted description
Interpretation impacted Not Applicable
Interpretation impacted description