The method quality of cross-over studies involved in Cochrane Systematic Reviews

Ref ID 676
First Author H. Ding
Journal PLOS ONE
Year Of Publishing 2015
URL https://dx.doi.org/10.1371/journal.pone.0120519
Keywords • Cochrane
• Risk of bias
• General medical
Problem(s) • Flawed risk of bias undertaken
Number of systematic reviews included 60
Summary of Findings None of the included reviews undertook a risk of bias assessment specific for the included cross-over studies. Items specific for cross-over studies were seldom considered anywhere in quality assessment of the reviews. When the authors reassessed the risk of bias, including 3 items specific to cross-over trials, a low risk of bias was judged for appropriate cross-over design in 79%, carry-over effects in 34% and for reporting data in all stages of the trial in 82%.
Did the article find that the problem(s) led to qualitative changes in interpretation of the results? N/A
Are the methods of the article described in enough detail to replicate the study? Yes