Limitations of Conclusions of Systematic Review and MetA-Analysis Because of Exclusion of Groups Most at Risk

Ref ID 677
First Author A.C.E. Dissevelt
Journal JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
Year Of Publishing 2017
URL http://dx.doi.org/10.1111/jgs.14656
Keywords • Pharmacological
• Mental health
• Cognition
• External validity
Problem(s) • Overly stringent inclusion criteria affecting external validity
Article Type Editorial
Article Subtype Comment/letter
First Author Country The Netherlands
Aim A letter highlighting the conduct of one systematic review of antipsychotic medication for delirium in hospitalised adults.
Level of Investigation Descriptive
Summary of Findings The author highlights that the review excluded individuals with dementia or stroke, those who had undergone neurosurgery or trauma, and those in nursing home and other nonhospital settings (e.g., rehabilitation, hospice, outpatient, emergency department). The author questions the validity of this decision as these groups are most at risk of developing delirium.
Number of systematic reviews included 1
Number of eligible systematic reviews assessed 1
Treatment impacted No
Treatment impacted description
Interpretation impacted Not Applicable
Interpretation impacted description