| Ref ID | 72 |
| First Author | C. Wayant |
| Journal | JOURNAL OF GENERAL INTERNAL MEDICINE |
| Year Of Publishing | 2020 |
| URL | https://pubmed.ncbi.nlm.nih.gov/31950401/ |
| Keywords |
• Oncology • Protocols • Pre-specification |
| Problem(s) |
• No registered or published protocol • Lack of prespecification in eligibility criteria • High risk of bias (ROBIS) |
| Article Type | Empirical |
| Article Subtype | Cross-sectional survey/Methodological systematic review |
| First Author Country | United States |
| Checklists |
• PRISMA 2009 • ROBIS |
| Aim | To assess the reporting quality (PRISMA) and risk of bias of systematic reviews (ROBIS) of colorectal cancer cited in the US National Comprehensive Cancer Network (NCCN) guidelines for the treatment of colon between 2011 and 2019. |
| Level of Investigation | Descriptive |
| Summary of Findings | Using ROBIS, only 3 (4.8%) of the included 63 systematic reviews were judged with low risk of bias, 35 (55.6%) systematic reviews were judged with unclear risk of bias, and 25 (39.7%) systematic reviews were judged with high risk of bias. Across all systematic reviews, the individual bias domains at the highest risk of bias were domains 1 (protocol and eligibility criteria) and 2 (methods to identify and select studies). Across all studies, the median adherence to PRISMA was 74.1% (IQR 69.2–80.0%), corresponding to approximately 20 of 27 items. |
| Number of systematic reviews included | 63 |
| Number of eligible systematic reviews assessed | 224 |
| Treatment impacted | No |
| Treatment impacted description | |
| Interpretation impacted | Not Applicable |
| Interpretation impacted description |