Cochrane vertebroplasty review misrepresented evidence for vertebroplasty with early intervention in severely affected patients

Ref ID 736
First Author W. Clark
Journal BMJ EVIDENCE-BASED MEDICINE
Year Of Publishing 2020
URL https://pubmed.ncbi.nlm.nih.gov/30852489/
Keywords • Cochrane
• Author
• Allegiance
• Influence
• Radiology
Problem(s) • Weaknesses identified in some Cochrane reviews
• Flawed risk of bias undertaken
• Non-financial conflicts of interest of review authors
• Inadequate analysis of heterogeneity
Article Type Editorial
Article Subtype Discussion piece
First Author Country Australia
Aim A discussion piece highlighting concerns over a Cochrane review of percutaneous vertebroplasty for osteoporotic vertebral compression fracture published in 2018.
Level of Investigation Descriptive
Summary of Findings The authors of the discussion piece highlight several concerns over a revised Cochrane review of percutaneous vertebroplasty for osteoporotic vertebral compression fracture published in 2018. The authors highlight that the first author of the review is a member of an independent non-statutory committee (MSAC), which appraises new medical services proposed for public funding (under ‘Medicare’) who was excluded from committee involvement due to conflict of interest, but not from the Cochrane review. Medicare funding was previously removed based on trials by authors of this Cochrane review. The authors argue that their study which is included in the Cochrane review is both misrepresented in data extraction and appraised unfairly for risk of bias.
Number of systematic reviews included 1
Number of eligible systematic reviews assessed 1