| Ref ID | 737 |
| First Author | L.Downie |
| Journal | JAMA OPHTHALMOLOGY |
| Year Of Publishing | 2018 |
| URL | https://pubmed.ncbi.nlm.nih.gov/29978192/ |
| Keywords |
• Cochrane • Ophthalmology • Disclosure • Low methodological quality • Non-Cochrane reviews • Low reporting quality • Protocols |
| Problem(s) |
• No registered or published protocol • Low methodological (AMSTAR) quality • Low reporting (PRISMA) quality • Conflicts of interest or funding of included studies not assessed • Funding or sponsor of systematic review not reported • Cochrane reviews more rigorous/higher quality than non-Cochrane reviews • Conflict of interest statement or disclosures for review authors missing |
| Article Type | Empirical |
| Article Subtype | Cross-sectional survey/Methodological systematic review |
| First Author Country | Australia |
| Checklists |
• AMSTAR 1 |
| Aim | To assess the reporting quality (PRISMA) and the methodological quality (AMSTAR) of systematic reviews of age-related macular degeneration published up to March 2017. |
| Level of Investigation | Analytical |
| Summary of Findings | Methodological quality of the 71 included systematic reviews of age-related macular degeneration published up to March 2017 was highly variable. The mean (SD) AMSTAR score was 5.8 (3.2) of 11.0, with no significant improvement over time (r = −0.03; 95%CI, −0.26 to 0.21; P = .83). Cochrane systematic reviews were overall of higher quality than reviews in other journals (mean [SD] AMSTAR score, 9.9 [1.2], n = 15 vs 4.7 [2.2], n = 56; P < .001). Overall, there was poor adherence to referring to an a priori design (22 articles [31%]) and reporting conflicts of interest in both the review and included studies (16 articles [23%]). Reviews funded by government grants and/or institutions were generally of higher quality than industry-sponsored reviews or where the funding source was not reported. |
| Number of systematic reviews included | 71 |
| Number of eligible systematic reviews assessed | 712 |
| Treatment impacted | No |
| Treatment impacted description | |
| Interpretation impacted | Not Applicable |
| Interpretation impacted description |