| Ref ID | 746 |
| First Author | L. Timmermans |
| Journal | ANNALS OF SURGERY |
| Year Of Publishing | 2014 |
| URL | https://pubmed.ncbi.nlm.nih.gov/24253146/ |
| Keywords |
• Surgery • Heterogeneity • Low reporting quality |
| Problem(s) |
• Intervention not described / defined • Inadequate analysis of heterogeneity |
| Article Type | Editorial |
| Article Subtype | Comment/letter |
| First Author Country | The Netherlands |
| Aim | A letter highlighting concerns over the conduct of one systematic review and meta-analysis of triclosan-impregnated sutures on surgical site infection and/or wound breakdown published in 2012. |
| Level of Investigation | Descriptive |
| Summary of Findings | The authors of the letters highlight that the randomised controlled trials included in the meta-analysis are highly heterogenous with regards to interventions, types of surgery (cerebrospinal fluid to breast surgery) and patient characteristics (adults and children). The differences between trials highlighted by the letter authors call into question the validity of the meta-analysis and conclusion. |
| Number of systematic reviews included | 1 |
| Number of eligible systematic reviews assessed | 1 |
| Treatment impacted | No |
| Treatment impacted description | |
| Interpretation impacted | Not Applicable |
| Interpretation impacted description |