| Ref ID | 777 |
| First Author | R. Jayaraj |
| Journal | ORAL ONCOLOGY |
| Year Of Publishing | 2019 |
| URL | http://dx.doi.org/10.1016/j.oraloncology.2018.12.018 |
| Keywords |
• External validity • Protocols • Transparency • Oncology • Immunology |
| Problem(s) |
• Ignores setting or context of included studies which limits review applicability • No registered or published protocol |
| Article Type | Editorial |
| Article Subtype | Comment/letter |
| First Author Country | Australia |
| Aim | A letter highlighting concerns over the conduct of one systematic review of PD-L1 expression for survival in head and neck squamous cell carcinoma published in 2018. |
| Level of Investigation | Descriptive |
| Summary of Findings | The authors of the letter highlight that a systematic review of PD-L1 expression for survival in head and neck squamous cell carcinoma published in 2018 did not provide a protocol or register with PRSOPERO to enable the methods of the review to be replicated and that exclusion criteria were applied to the clinical topic which limited the applicability of the results. |
| Number of systematic reviews included | 1 |
| Number of eligible systematic reviews assessed | 1 |
| Treatment impacted | No |
| Treatment impacted description | |
| Interpretation impacted | Not Applicable |
| Interpretation impacted description |