| Ref ID | 782 |
| First Author | E. Igelstrom |
| Journal | JOURNAL OF CLINICAL EPIDEMIOLOGY |
| Year Of Publishing | 2021 |
| URL | https://www.sciencedirect.com/science/article/pii/S0895435621002675 |
| Keywords |
• Low methodological quality • General medical • Observational studies |
| Problem(s) |
• Inclusion of observational / non-randomised studies • Flawed risk of bias undertaken • Low methodological (AMSTAR) quality |
| Article Type | Empirical |
| Article Subtype | Cross-sectional survey/Methodological systematic review |
| First Author Country | United Kingdom |
| Aim | To assess the use of the ‘Risk of Bias In Non-randomized Studies–of Interventions’ (ROBINS-I), a Cochrane risk of bias assessment tool, has been used in systematic reviews published between January 01 2020 to March 02, 2020. |
| Level of Investigation | Analytical |
| Summary of Findings | From 93 included systematic reviews indexed across Scopus, Web of Science, MEDLINE, Embase, and the Cochrane Database of Systematic Reviews between January 01 2020 to March 02, 2020. Quality of reviews (AMSTAR-2) was mostly low, and modifications and incorrect use of ROBINS-I were common, with 20% reviews modifying the rating scale, 20% understating overall risk of bias, and 19% including critical-risk of bias studies in evidence synthesis. Poorly conducted reviews were more likely to report low/moderate risk of bias (predicted probability 57% [95% CI: 47–67] in critically low-quality reviews, 31% [19–46] in high/moderate-quality reviews). |
| Number of systematic reviews included | 93 |
| Number of eligible systematic reviews assessed | 181 |
| Treatment impacted | No |
| Treatment impacted description | |
| Interpretation impacted | Not Applicable |
| Interpretation impacted description |