| Ref ID | 794 |
| First Author | S. Ferrell |
| Journal | JOURNAL OF SUBSTANCE ABUSE TREATMENT |
| Year Of Publishing | 2022 |
| URL | https://www.sciencedirect.com/science/article/pii/S074054722100324X?casa_token=-pmNQ951B7EAAAAA:mzYhL1CUB2jt_ftZp4Mc8KHSJHhkgfWsDUVQDQHRmpxeF269Itngxk3jZ8AXo7X_ptAX6Sy1qLw |
| Keywords |
• Disclosure • Sponsorship bias • Allegiance • Pain • Author • Non-Cochrane reviews |
| Problem(s) |
• Conflict of interest statement or disclosures for review authors missing • Non-financial conflicts of interest of review authors • Financial conflicts of interest of review authors |
| Article Type | Empirical |
| Article Subtype | Meta-epidemiological analysis |
| First Author Country | United States |
| Aim | To assess the prevalence of conflicts of interest in systematic reviews of opioid use published across 3 databases up to June 2 2020, and the interaction between presence of conflicts and favourability of results. |
| Level of Investigation | Analytical |
| Summary of Findings | From 17 systematic reviews of opioid use published across 3 databases up to June 2 2020, 25 authors (30.9%) had some form of conflict of interest, and 22 (of 25, 88.0%) authors had an undisclosed conflict of interest. However, no significant association existed between conflicts of interest and favourability of results and conclusions. Notably, two systematic reviews (of 17; 11.76%) were industry-sponsored. No association was found between the study sponsor source and the favourability of systematic review results and conclusions. |
| Number of systematic reviews included | 17 |
| Number of eligible systematic reviews assessed | 1021 |
| Treatment impacted | Yes |
| Treatment impacted description | The interaction between presence of conflicts and favourability of results was assessed. |
| Interpretation impacted | No |
| Interpretation impacted description |