| Ref ID | 795 |
| First Author | A. Corcoran |
| Journal | ANDROLOGY |
| Year Of Publishing | 2021 |
| URL | https://onlinelibrary.wiley.com/doi/full/10.1111/andr.13064 |
| Keywords |
• Endocrinology • Disclosure • Non-Cochrane reviews • Sponsorship bias • Allegiance • Transparency |
| Problem(s) |
• Conflict of interest statement or disclosures for review authors missing • Financial conflicts of interest of review authors |
| Article Type | Empirical |
| Article Subtype | Meta-epidemiological analysis |
| First Author Country | United States |
| Aim | To assess whether author conflicts of interest and industry sponsorship influenced the nature of results and conclusions of systematic reviews of treatment interventions for erectile dysfunction indexed in PubMed and Embase between September 1, 2016, and June 2, 2020. |
| Level of Investigation | Analytical |
| Summary of Findings | From 23 included systematic reviews of treatment interventions for erectile dysfunction indexed in PubMed and Embase between September 1, 2016, and June 2, 2020. Nineteen authors (13.8%) were found to have conflicts of interest (disclosed, undisclosed, or both). No authors completely disclosed all conflicts. Nine reviews (37.5%) contained at least one author with conflicts of interest; of which eight reported narrative results favouring the treatment group, and seven reported conclusions favouring the treatment group. Of the 15 (62.5%) reviews without a conflicted author, 11 reported results favouring the treatment group, and 12 reported conclusions favouring the treatment group. |
| Number of systematic reviews included | 24 |
| Number of eligible systematic reviews assessed | 2224 |
| Treatment impacted | Yes |
| Treatment impacted description | The results and conclusions of systematic reviews for erectile dysfunction treatments did not appear to be influenced by authors who reported conflicts of interest. |
| Interpretation impacted | No |
| Interpretation impacted description |