| Ref ID | 842 |
| First Author | R. Bajpai |
| Journal | QJM |
| Year Of Publishing | 2023 |
| URL | https://academic.oup.com/qjmed/article/116/5/406/6647866?login=true |
| Keywords |
• Reproducibility • Protocols • Heterogeneity • Low reporting quality • COVID • Vitamins and supplements • Non-Cochrane reviews |
| Problem(s) |
• No registered or published protocol • Low reporting (PRISMA) quality • Methods not described to enable replication • Inadequate analysis of heterogeneity |
| Article Type | Editorial |
| Article Subtype | Comment/letter |
| First Author Country | United Kindgom |
| Aim | To highlight problems in the conduct of a systematic review examining the effect of Vitamin D supplementation on the severity of COVID-19. |
| Level of Investigation | Descriptive |
| Summary of Findings | From a letter highlighting problems in the conduct of a systematic review examining the effect of Vitamin D supplementation on the severity of COVID-19 published in 2022. Several methodological issues were reported to be identified relating to planning (no information on PROSPERO), conduct (non-reproducible literature search), analytical methods (misleading and biased analysis plan) and reporting (not following PRISMA checklist) that the letter author argues limits the acceptability and generalizability of the findings from the review and could mislead clinical decision-making. |
| Number of systematic reviews included | 1 |
| Number of eligible systematic reviews assessed | 1 |
| Treatment impacted | No |
| Treatment impacted description | |
| Interpretation impacted | Not Applicable |
| Interpretation impacted description |