| Ref ID | 858 |
| First Author | F. Crawford |
| Journal | BMC MEDICAL RESEARCH METHODOLOGY |
| Year Of Publishing | 2022 |
| URL | https://bmcmedresmethodol.biomedcentral.com/articles/10.1186/s12874-022-01738-y |
| Keywords |
• Expertise • Reproducibility • Low reporting quality • Searching • Low methodological quality • Risk of bias • Endocrinology |
| Problem(s) |
• High risk of bias (ROBIS) • Lack of prespecification in eligibility criteria • Insufficient literature searches • Lack of statistical expertise in handling of quantitative data • Poor execution of narrative synthesis |
| Article Type | Empirical |
| Article Subtype | Cross-sectional survey/Methodological systematic review |
| First Author Country | United Kingdom |
| Checklists |
• ROBIS |
| Aim | To assess the comprehensiveness and utility of the available secondary evidence as a reliable source of robust estimates of effect with the aim of informing a cost-effective care pathway using an economic model. |
| Level of Investigation | Descriptive |
| Summary of Findings | From 30 included systematic reviews of foot ulcer prevention in diabetes indexed across 6 databases up to 17th May 2021. Many of the 30 included systematic reviews were poorly reported and have fundamental methodological shortcomings (assessed using ROBIS) associated with increased risk of bias. Most concerns relate to vague inclusion criteria (60%), weak search or selection strategies (70%) and quality appraisal methods (53%) and inexpert conduct and interpretation of quantitative and narrative evidence syntheses (57%). |
| Number of systematic reviews included | 30 |
| Number of eligible systematic reviews assessed | 8980 |
| Treatment impacted | No |
| Treatment impacted description | |
| Interpretation impacted | Not Applicable |
| Interpretation impacted description |