| Ref ID | 903 |
| First Author | S.P. Riley |
| Journal | JOURNAL OF MANUAL & MANIPULATIVE THERAPY |
| Year Of Publishing | 2022 |
| URL | https://www.tandfonline.com/doi/full/10.1080/10669817.2022.2110419 |
| Keywords |
• Low methodological quality • Protocols • Non-Cochrane reviews • Musculoskeletal • Pre-specification • Transparency |
| Problem(s) |
• Lack of prespecification in eligibility criteria • Reasons for excluding potentially eligible studies not provided • Conflicts of interest or funding of included studies not assessed • Low methodological (AMSTAR) quality • No registered or published protocol • Undocumented or unjustified deviations to the review protocol |
| Article Type | Empirical |
| Article Subtype | Cross-sectional survey/Methodological systematic review |
| First Author Country | United States |
| Checklists |
• AMSTAR 2 |
| Aim | To establish if verified prospective registration of systematic reviews (SRs) and the randomized clinical trials (RCTs) that they use affect an SR’s methodological quality on AMSTAR 2. |
| Level of Investigation | Descriptive |
| Summary of Findings | From twenty included musculoskeletal systematic reviews indexed in MEDLINE, between 1 January 2018 and 18 August 2021. One (5.0%) of the 20 included reviews were prospectively registered and published. Of these, 13 (65.0%) were registered through PROSPERO, 2 (15.4%) prospectively, and 11 retrospectively. Nineteen (95.0%) of the 20 identified systematic reviews was categorized as ‘critically low’ methodological quality (AMSTAR 2). The AMSTAR-2 items that were least reported were: availability or deviation from a protocol; authors explaining their selection of the study designs for inclusion; authors providing a list of excluded studies and justify the exclusions; authors reporting on the sources of funding for the studies included in the review. |
| Number of systematic reviews included | 20 |
| Number of eligible systematic reviews assessed | 703 |
| Treatment impacted | No |
| Treatment impacted description | |
| Interpretation impacted | Not Applicable |
| Interpretation impacted description |