Substantial heterogeneity found in reporting mortality in Cochrane systematic reviews and Core Outcome Sets in COMET database

Ref ID	913
First Author	E. Tomlinson
Journal	JOURNAL OF CLINICAL EPIDEMIOLOGY
Year Of Publishing	2022
URL	https://www.sciencedirect.com/science/article/pii/S0895435622000142?via%3Dihub
Keywords	• Cochrane • Outcomes • Multiplicity • Pre-specification
Problem(s)	• Weaknesses identified in some Cochrane reviews • Multiplicity of outcomes and lack of pre-specification for outcome reporting
Number of systematic reviews included	1978
Summary of Findings	From 1978 included Cochrane systematic reviews that included mortality as an outcome published January 2015-March 2021. There were 2,454 mortality outcomes were reported in 49% (1978/3999) of Cochrane reviews: all-cause (37%), infant (23%), maternal (11%), survival (10%), cause-specific (9%). Due to reviews not specifying mortality outcome type or including studies reporting no data, 11% (273/2208) remained uncategorized. Infant mortality and maternal mortality were frequently used together in reviews reporting two mortality outcomes.
Did the article find that the problem(s) led to qualitative changes in interpretation of the results?	N/A
Are the methods of the article described in enough detail to replicate the study?	No