Effectiveness of nonpharmacological interventions to prevent adverse events in the intensive care unit: A review of systematic reviews

Ref ID 923
First Author S. Suclupe
Journal AUSTRALIAN CRITICAL CARE
Year Of Publishing 2022
URL https://dx.doi.org/10.1016/j.aucc.2022.11.003
Keywords • Low methodological quality
• Searching
• General medical
• Transparency
• Protocols
• Pre-specification
• Harms
Problem(s) • Insufficient literature searches
• Lack of prespecification in eligibility criteria
• Reasons for excluding potentially eligible studies not provided
• No registered or published protocol
• Low methodological (AMSTAR) quality
Article Type Empirical
Article Subtype Cross-sectional survey/Methodological systematic review
First Author Country Spain
Checklists • AMSTAR 2
• GRADE
Aim To provide an overview of effectiveness nonpharmacological interventions aimed at preventing adverse events in the intensive care unit.
Level of Investigation Descriptive
Summary of Findings From 37 included systematic reviews of nonpharmacological interventions for preventing adverse events in the intensive care unit, indexed across PubMed, CINAHL, and Cochrane Library up to March 2022. Twenty-eight of thirty seven (75.6%) systematic reviews scored critically low on methodological quality and six (16.2%) systematic reviews scored low. The main deficiencies noted were: 1) failure to report a prior registered protocol 2) adequacy of the literature search 3) justification for excluding studies 4) reasons for study design selection and 5) describing the included studies in adequate detail. None of the included systematic reviews fulfilled all the AMSTAR-2 criteria. Regarding the certainty of the evidence, only six (16.2%) systematic reviews reported the certainty of evidence for the primary outcomes.
Number of systematic reviews included 37
Number of eligible systematic reviews assessed 3225
Treatment impacted No
Treatment impacted description
Interpretation impacted Not Applicable
Interpretation impacted description