Is data missing? An assessment of publication bias in orthodontic systematic reviews from 2010 to 2021

Ref ID 942
First Author F. Mikelis
Journal EUROPEAN JOURNAL OF ORTHODONTICS
Year Of Publishing 2022
URL https://academic.oup.com/ejo/article/44/4/468/6527159?login=true
Keywords • Non-Cochrane reviews
• Publication bias
• Dentistry
• Grey literature
Problem(s) • Poor consideration of publication bias
• Grey literature excluded
Article Type Empirical
Article Subtype Cross-sectional survey/Methodological systematic review
First Author Country Greece
Aim To assess the extent of publication bias assessment in systematic reviews across the orthodontic literature indexed in the Cochrane Database of Systematic Reviews, from January 2010, until November 2021.
Level of Investigation Descriptive
Summary of Findings From 289 included systematic reviews across the orthodontic literature indexed in the Cochrane Database of Systematic Reviews, from January 2010, until November 2021. Efforts to search within unpublished literature were reported in 191 out of 289 Reviews (66.1%), while efforts to communicate with primary study authors were recorded for 150 of 289 of those (51.9%). An appropriate strategy plan to address issues of publication bias, conditional on the number of studies available and the methodology plan reported, was followed in 78 of the 139 meta-analyses (56.1%). Formal publication bias assessment was actually reported in 35 of 139 meta-analyses (25.2%), while only half of those (19/35; 54.3%) followed an appropriately established methodology. Ten of the latter 19 studies detected the presence of publication bias (52.6%). Predictor variables of appropriate publication bias assessment did not reveal any significant effects.
Number of systematic reviews included 289
Number of eligible systematic reviews assessed 322
Treatment impacted No
Treatment impacted description
Interpretation impacted Not Applicable
Interpretation impacted description