Inflexible methods to complex questions

Articles that support this problem:

Outcomes in systematic reviews of complex interventions never reached “high” GRADE ratings when compared with those of simple interventions

2016 : Journal of clinical epidemiology

Systematic mixed-methods reviews are not ready to be assessed with the available tools

2011 : Journal of clinical epidemiology

Cluster Randomised Trials in Cochrane Reviews: Evaluation of Methodological and Reporting Practice

2016 : Plos one

Assessing the applicability of findings in systematic reviews of complex interventions can enhance the utility of reviews for decision making

2013 : Journal of clinical epidemiology

Few systematic reviews exist documenting the extent of bias: a systematic review

2008 : Journal of clinical epidemiology

Validity of a Cochrane Systematic Review and meta-analysis for determining the safety of vitamin E

2017 : Bmc complementary & alternative medicine

Why are Cochrane hepato-biliary reviews undervalued by physicians as an aid for clinical decision-making?

2010 : Digestive and liver disease

Contradictory Findings of Two Recent Meta-Analyses: What Are We Supposed to Believe About Anesthetic Technique in Patients Undergoing Cardiac Surgery?

2021 : Journal of cardiothoracic and vascular anesthesia