- Framework of problems / Rigourous
- Errors in effect estimate calculations or data synthesis
- Reliability of the Evidence Addressing Treatment of Corneal Diseases: A Summary of Systematic Reviews
| Ref ID | 100 |
| First Author | I. J. Saldanha |
| Journal | JAMA OPHTHALMOLOGY |
| Year Of Publishing | 2019 |
| URL | https://jamanetwork.com/journals/jamaophthalmology/articlepdf/2732698/jamaophthalmology_saldanha_2019_oi_190021.pdf |
| Keywords |
• Ophthalmology • Cochrane • Risk of bias • Searching • Error |
| Problem(s) |
• Insufficient literature searches • Errors in effect estimate calculations or data synthesis • Limited quality assessment or no risk of bias |
| Number of systematic reviews included | 98 |
| Summary of Findings | Thirty-three of the included 98 systematic reviews (34%) were classified as unreliable. The most frequent reasons for unreliability were that the systematic review did not conduct a comprehensive literature search for studies (22 of 33 [67%]), did not assess risk of bias of the individual included studies (13 of 33 [39%]), and did not use appropriate methods for quantitative syntheses (meta-analysis) (12 of 17 systematic reviews that conducted a quantitative synthesis [71%]). |
| Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | N/A |
| Are the methods of the article described in enough detail to replicate the study? | No |