Comparison of search strategies in systematic reviews of adverse effects to other systematic reviews

Ref ID 123
First Author S. Golder
Journal HEALTH INFORMATION & LIBRARIES JOURNAL
Year Of Publishing 2014
URL https://pubmed.ncbi.nlm.nih.gov/24754741/
Keywords • Harms
• Cochrane
• Searching
• Reproducibility
Problem(s) • Insufficient literature searches
• Reliance on randomised controlled trials for harms / safety data
• Methods not described to enable replication
• Search strategy not provided
Article Type Empirical
Article Subtype Cross-sectional survey/Methodological systematic review
First Author Country United Kingdom
Aim To compare search methods in systematic reviews of adverse effects with other reviews from a sample published in the Cochrane Database of Systematic Reviews (Issue 6:2011) and the Database of Abstracts of Reviews of Effects website (June 2011).
Level of Investigation Descriptive
Summary of Findings From 849 systematic reviews dated from 1994 to 2011. A third of reviews (280/849, 33%) limited themselves to data from randomised controlled trials. Adverse effects search terms were used by 72% of reviews and despite recommendations only two reviews report using floating subheadings. 19% of all reviews only searched MEDLINE. Only 74/849 (9%) provided sufficient detail to allow the search to be reproduced.
Number of systematic reviews included 849
Number of eligible systematic reviews assessed 15718
Treatment impacted No
Treatment impacted description
Interpretation impacted Not Applicable
Interpretation impacted description