- Framework of problems / Transparent
- Multiplicity of outcomes and lack of pre-specification for outcome reporting
- Outcome reporting bias in Cochrane systematic reviews: a cross-sectional analysis
| Ref ID | 130 |
| First Author | K. Shah |
| Journal | BMJ OPEN |
| Year Of Publishing | 2020 |
| URL | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076244/pdf/bmjopen-2019-032497.pdf |
| Keywords |
• Cochrane • Multiplicity • General medical • Protocols • Pre-specification |
| Problem(s) |
• Undocumented or unjustified deviations to the review protocol • Multiplicity of outcomes and lack of pre-specification for outcome reporting |
| Number of systematic reviews included | 350 |
| Summary of Findings | Of the 350 included Cochrane reviews, 150 (43%) review and protocol pairings contained discrepancies in outcome reporting. When reviews were further scrutinised, 23% (35 of 150) of reviews with discrepancies in outcome reporting contained a high risk of outcome reporting bias, with changes being made after knowledge of results from individual trials. |
| Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | N/A |
| Are the methods of the article described in enough detail to replicate the study? | Yes |