- Framework of problems / Rigourous
- Risk of bias not incorporated into conclusions of review
- Financial conflicts of interest and conclusions about neuraminidase inhibitors for influenza: an analysis of systematic reviews
| Ref ID | 157 |
| First Author | A. G. Dunn |
| Journal | ANNALS OF INTERNAL MEDICINE |
| Year Of Publishing | 2014 |
| URL | https://pubmed.ncbi.nlm.nih.gov/25285542/ |
| Keywords |
• Immunology • Influence • Allegiance • Author • Risk of bias • Sponsorship bias |
| Problem(s) |
• Risk of bias not incorporated into conclusions of review • Financial conflicts of interest of review authors |
| Number of systematic reviews included | 26 |
| Summary of Findings | Data from 26 included systematic reviews of neuraminidase inhibitors for influenza published between 2005 and 2014 were subject to dual blind inter-agreement. Among assessments associated with a financial conflict of interest, 7 of 8 (88%) were classified as favourable, compared with 5 of 29 (17%) among those without a financial conflict of interest. Reviewers without financial conflicts of interest were more likely to include statements about the quality and validity of the primary studies (15 of 19; 79%) than those with financial conflicts of interest (1 of 7; 14%). |
| Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | Yes |
| Are the methods of the article described in enough detail to replicate the study? | Yes |