Incomplete Systematic Meta-analysis of Pharmacological Therapies for Opioid-Induced Constipation

Ref ID 192
First Author N. Katakami
Journal JOURNAL OF PAIN & SYMPTOM MANAGEMENT
Year Of Publishing 2018
URL https://www.jpsmjournal.com/article/S0885-3924(18)30125-8/pdf
Keywords • Pain
• Missing data
Problem(s) • Errors in study inclusion or omission of relevant studies
Article Type Editorial
Article Subtype Comment/letter
First Author Country Japan
Aim A letter to the editor highlighting flaws in the conduct of one systematic review of drugs for treating opioid-induced constipation published in 2018.
Level of Investigation Descriptive
Summary of Findings The author highlights that two relevant studies were erroneously missed from the systematic review and that inclusion of these studies are likely to impact the findings of the subsequent meta-analysis. The authors of the systematic review in question reply to the letter to confirm that the studies were inexplicably missed and the review requires updating.
Number of systematic reviews included 1
Number of eligible systematic reviews assessed 1
Treatment impacted No
Treatment impacted description
Interpretation impacted Not Applicable
Interpretation impacted description