- Framework of problems / Transparent
- Failure to address missing outcome data in analyses
- Effects of drop-out on efficacy estimates in five Cochrane reviews of popular antipsychotics for schizophrenia
| Ref ID | 297 |
| First Author | P. Hutton |
| Journal | ACTA PSYCHIATRICA SCANDINAVICA |
| Year Of Publishing | 2012 |
| URL | https://core.ac.uk/download/43706356.pdf |
| Keywords |
Cochrane Missing data Mental health Pharmacological |
| Problem(s) |
Failure to address missing outcome data in analyses |
| Number of systematic reviews included | 5 |
| Summary of Findings | All Cochrane reviews included a number of studies they said they had excluded, or intended to exclude, because of high levels of attrition. Several reviews also excluded data from a number of relatively low-attrition studies because of missing standard deviations. Five Cochrane reviews of five popular antipsychotics for schizophrenia misrepresented the available evidence on their efficacy. |
| Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | Yes |
| Are the methods of the article described in enough detail to replicate the study? | Yes |