Effects of drop-out on efficacy estimates in five Cochrane reviews of popular antipsychotics for schizophrenia

Ref ID 297
First Author P. Hutton
Year Of Publishing 2012
URL https://core.ac.uk/download/43706356.pdf
Keywords Cochrane
Missing data
Mental health
Problem(s) Failure to address missing outcome data in analyses
Number of systematic reviews included 5
Summary of Findings All Cochrane reviews included a number of studies they said they had excluded, or intended to exclude, because of high levels of attrition. Several reviews also excluded data from a number of relatively low-attrition studies because of missing standard deviations. Five Cochrane reviews of five popular antipsychotics for schizophrenia misrepresented the available evidence on their efficacy.
Did the article find that the problem(s) led to qualitative changes in interpretation of the results? Yes
Are the methods of the article described in enough detail to replicate the study? Yes