- Framework of problems / Comprehensive
- Reliance on randomised controlled trials for harms / safety data
- Most systematic reviews of adverse effects did not include unpublished data
|JOURNAL OF CLINICAL EPIDEMIOLOGY
|Year Of Publishing
Reliance on randomised controlled trials for harms / safety data
Grey literature excluded
|Number of systematic reviews included
|Summary of Findings
|Only 39% of all the included reviews searched a specific source for unpublished data, such as conference abstracts or trial registries, and nearly half of these reviews (48%) included unpublished data. Overall, 22% of reviews included unpublished data/studies
|Did the article find that the problem(s) led to qualitative changes in interpretation of the results?
|Are the methods of the article described in enough detail to replicate the study?