Most systematic reviews of adverse effects did not include unpublished data

Ref ID 374
First Author S. Golder
Year Of Publishing 2016
Keywords Grey literature
General medical
Problem(s) Reliance on randomised controlled trials for harms / safety data
Grey literature excluded
Number of systematic reviews included 348
Summary of Findings Only 39% of all the included reviews searched a specific source for unpublished data, such as conference abstracts or trial registries, and nearly half of these reviews (48%) included unpublished data. Overall, 22% of reviews included unpublished data/studies
Did the article find that the problem(s) led to qualitative changes in interpretation of the results? Not Applicable
Are the methods of the article described in enough detail to replicate the study? No