Some improvements are apparent in identifying adverse effects in systematic reviews from 1994 to 2011

Ref ID 376
First Author S. Golder
Year Of Publishing 2013
Keywords Cochrane
Problem(s) Reliance on randomised controlled trials for harms / safety data
Methods not described to enable replication
Number of systematic reviews included 849
Summary of Findings 5% of reviews in the Cochrane database and the Database of abstract of reviews of effects between 1994 and 2011 focused on adverse effects. Whilst some improvements in literature searches were apparent, such as an increase in the number of databases searched and fewer date and language restrictions applied there was an increase in reviews limited to data from randomized controlled trials. The reporting of search strategies could still be improved further, with only 9% of the included reviews reporting reproducible searches.
Did the article find that the problem(s) led to qualitative changes in interpretation of the results? Not Applicable
Are the methods of the article described in enough detail to replicate the study? Yes