Susceptibility to fraud in systematic reviews: lessons from the Reuben case

Ref ID 38
First Author E. Marret
Journal ANESTHESIOLOGY
Year Of Publishing 2009
URL https://watermark.silverchair.com/0000542-200912000-00023.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAs8wggLLBgkqhkiG9w0BBwagggK8MIICuAIBADCCArEGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMxveAUZWgEvcdUeHlAgEQgIICgk7QVNPVKO2kE6TYVlgsXC5g3mZ7Jw9wl2SqkyCDJf-6nYMYHiOOQ1e8PLsaTmJLHY2FaiDeqLj3GhUVp2e3u0xTvYFOWKyPoVfBZKl7aN9oe2nBvDRkxOztfq1WGxrRdbTkxqhQ31wy7k-cuzzu4YB9qbW4m5tv6FDakFKM3-jWlCnUroomcFO0NplFON6kzPt0vgQ85aPrDe6k1LnjDVcJV5gs82nftivdbon64bRwDueSWJ_6WwXfyILDtlVNUKBB7llV2YHSaneeksqIBquGG6YpqgqsG-yTkiLRMv_r4X-qMywSqSuBCNxqtRtnJcYF35Ngh1eBN1zI9nnbqDApCVanlJ-ObO1S8kJ0l4944xqNWdl-Fv6pRkdxR4h5RCevr51FQ2xdb92ZGD4YhAgTN-7VDrI1IGEyadUTgLH4JAc1uzVaW7Mrt54OJnsZ7SasrCRVMwr3r87bcnhFdKiYgYA7-iPy3GHCL5noHHQ_X_wJ_VFU3gPITIFrJ2SyFzOIZWGSrZg0hCxZ2CmCrsho6z-dUimTtFFYu96BoY4jjTNIElSNadwFz2J5U4TyaoXGp57XIQz1gorQzsgYs86bYasLWbLRaMmVI5f08ki3b3w3CLB00DHO2YOxj04N7NZ1k3oy5nPGNkBziLTV27U0TDJAl3BIqH17KcvtaykjuCQJMTfH2hg82jSkAnIgM8iPHl4odvHsUz_BouAdSRDgjQ-RntPRDBhW4I7F1Wc8DgpH2FT2yUzsC7z6jJVFJtvhsjiLzK7-K-c2T90Ym-dpb0xEE8038VqheIcy5_ZNiOTjBYI6sr2tyHDIo5rhNWz-2_z1nzut2RnGXnbuZceglg
Keywords Surgery
Pain
Misconduct
Retraction
Problem(s) Perpetuates citation of poor quality primary study data
Number of systematic reviews included 25
Summary of Findings From 25 systematic reviews that included falsified data. One of 6 quantitative reviews which included Reuben reports would have reached different conclusions without Reuben reports. In all 6 (30 subgroup analyses involving Reuben reports), exclusion of Reuben reports never made any difference when the number of patients from Reuben reports was less than 30% of all patients included in the analysis. Of 8 qualitative reviews which included Reuben reports, all authors agreed that one would certainly have reached different conclusions without Reuben reports. For another 4, the authors’ judgment was not unanimous.
Did the article find that the problem(s) led to qualitative changes in interpretation of the results? Yes
Are the methods of the article described in enough detail to replicate the study? Yes