- Framework of problems / Objective
- Inflexible methods to complex questions
- Assessing the applicability of findings in systematic reviews of complex interventions can enhance the utility of reviews for decision making
| Ref ID | 391 |
| First Author | B. Burford |
| Journal | JOURNAL OF CLINICAL EPIDEMIOLOGY |
| Year Of Publishing | 2013 |
| URL | https://www.jclinepi.com/article/S0895-4356(13)00263-1/fulltext |
| Keywords |
External validity General medical |
| Problem(s) |
Ignores setting or context of included studies which limits review applicability Inflexible methods to complex questions |
| Number of systematic reviews included | 3 |
| Summary of Findings | Discusses challenges and opportunities of ensuring applicability of systematic reviews using three published examples of reviews of complex interventions. Recommendations include: Better description of population characteristics in primary studies, interventions, Use of qualitative evidence syntheses and logic models to generate hypotheses regarding the effects of intervention variation; Planned subgroup analyses/meta-regression to explore interactions between intervention variants and effects; Summarize effect sizes across outcome categories using the ‘‘median of medians’’ approach or other approaches that do not require statistical pooling of data |
| Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | Not Applicable |
| Are the methods of the article described in enough detail to replicate the study? | No |