Assessing harmful effects in systematic reviews

Ref ID 431
First Author H. M. McIntosh
Year Of Publishing 2004
Keywords Harms
Risk of bias
Problem(s) Reliance on randomised controlled trials for harms / safety data
Review question not justified / important
Limited quality assessment or no risk of bias
Number of systematic reviews included 3
Summary of Findings All three reviews generated a large volume of work that did not yield much useful information for health care decision makers. The key areas for improvement we identified were focusing the review question, including appropriate study designs for obtaining safety data and developing methods for quality assessment of studies of harmful effects.
Did the article find that the problem(s) led to qualitative changes in interpretation of the results? Not Applicable
Are the methods of the article described in enough detail to replicate the study? No