- Framework of problems / Transparent
- No registered or published protocol
- A systematic survey shows that reporting and handling of missing outcome data in networks of interventions is poor
Ref ID | 436 |
First Author | L. M. Spineli |
Journal | BMC MEDICAL RESEARCH METHODOLOGY |
Year Of Publishing | 2018 |
URL | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201503/pdf/12874_2018_Article_576.pdf |
Keywords |
Protocols Missing data Network meta-analysis General medical |
Problem(s) |
Failure to address missing outcome data in analyses No registered or published protocol |
Number of systematic reviews included | 387 |
Summary of Findings | 72% did not mention whether a protocol was available; 17% mentioned that a protocol was developed but they did not make the protocol available. Only 16% reviews explicitly defined (either in their protocol or publication) missing outcome data however 70% of reviews explicitly reported that there was missing outcome data in the included trials. 56% applied at least one strategy to address missing outcome data in their analysis. Overall, there was insufficient information in most systematic reviews with network meta-analysis to judge the actual strategy applied to handle missing outcome data. |
Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | Not Applicable |
Are the methods of the article described in enough detail to replicate the study? | Yes |