Registration of systematic reviews in PROSPERO: 30,000 records and counting

Ref ID 511
First Author M. J. Page
Journal SYSTEMATIC REVIEWS
Year Of Publishing 2018
URL https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819709/pdf/13643_2018_Article_699.pdf
Keywords Protocols
Multiplicity
Pre-specification
General medical
Problem(s) Multiplicity of outcomes and lack of pre-specification for outcome reporting
Number of systematic reviews included 150
Summary of Findings There was a 10-fold increase in registrations between 2012 (63 systematic reviews per month) to 2017 (800 per month). No information about the primary outcome other than the domain (e.g. timing, effect measures) was pre-specified in 29% of records.
Did the article find that the problem(s) led to qualitative changes in interpretation of the results? Not Applicable
Are the methods of the article described in enough detail to replicate the study? Yes