- Framework of problems / Transparent
- Multiplicity of outcomes and lack of pre-specification for outcome reporting
- Age-treatment subgroup analyses in Cochrane intervention reviews: a meta-epidemiological study
| Ref ID | 530 |
| First Author | P. Liu |
| Journal | BMC MEDICINE |
| Year Of Publishing | 2019 |
| URL | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805640/pdf/12916_2019_Article_1420.pdf |
| Keywords |
• Cochrane • General medical • Subgroup • Pre-specification • Multiplicity |
| Problem(s) |
• Unplanned or unjustified subgroup or sensitivity analyses • Multiplicity of outcomes and lack of pre-specification for outcome reporting |
| Number of systematic reviews included | 928 |
| Summary of Findings | 20.4% of the 928 included Cochrane reviews outlined plans to conduct age treatment subgroup analyses. However, 2.7% reviews actually reported age-treatment subgroup analyses. Three reviews performed unplanned age-treatment subgroup analyses. |
| Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | N/A |
| Are the methods of the article described in enough detail to replicate the study? | Yes |