- Framework of problems / Rigourous
- Unplanned or unjustified subgroup or sensitivity analyses
- Age-treatment subgroup analyses in Cochrane intervention reviews: a meta-epidemiological study
Ref ID | 530 |
First Author | P. Liu |
Journal | BMC MEDICINE |
Year Of Publishing | 2019 |
URL | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805640/pdf/12916_2019_Article_1420.pdf |
Keywords |
Cochrane Multiplicity Pre-specification Subgroup General medical |
Problem(s) |
Unplanned or unjustified subgroup or sensitivity analyses Multiplicity of outcomes and lack of pre-specification for outcome reporting |
Number of systematic reviews included | 928 |
Summary of Findings | 20.4% of the 928 included Cochrane reviews outlined plans to conduct age treatment subgroup analyses. However, 2.7% reviews actually reported age-treatment subgroup analyses. Three reviews performed unplanned age-treatment subgroup analyses. |
Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | Not Applicable |
Are the methods of the article described in enough detail to replicate the study? | Yes |