- Framework of problems / Rigourous
- Weaknesses identified in some Cochrane reviews
- The impact of study size on meta-analyses: examination of underpowered studies in Cochrane reviews
Ref ID | 545 |
First Author | R. M. Turner |
Journal | PLOS ONE |
Year Of Publishing | 2013 |
URL | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609745/pdf/pone.0059202.pdf |
Keywords |
Cochrane Power General medical |
Problem(s) |
Perpetuates citation of poor quality primary study data Weaknesses identified in some Cochrane reviews |
Number of systematic reviews included | 14886 |
Summary of Findings | In 70% of CDSR meta-analyses, all studies had less than 50% power to detect a 30% relative risk reduction, and only 17% of meta-analyses included at least two studies with at least 50% power to detect a relative risk reduction of 30%. |
Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | No |
Are the methods of the article described in enough detail to replicate the study? | Yes |